Description

Cispladn 50 (Cisplatin) 50 mg/50 ml, Solution for Injection — Full Product Description

Active ingredient: Cisplatin
Dosage form: Solution for injection
Strength: 50 mg/50 ml
Pharmacological group: Antineoplastic agents, platinum compounds
Route of administration: Intravenous
Manufacturer: Biozenta Lifesciences Pvt. Ltd.
Country of origin: India

---

Product Overview

Cispladn 50 is a cytotoxic antineoplastic medicinal product containing cisplatin, a widely used platinum-based chemotherapy agent in modern oncology. The medicine is included in numerous standardized chemotherapy regimens and is administered either as part of combination therapy or individualized treatment protocols depending on the clinical indication.

Cisplatin has demonstrated proven clinical efficacy and remains a cornerstone in the pharmacological treatment of various malignant neoplasms.

---

Mechanism of Action

Cisplatin exerts its antitumor effect by:

• forming cross-links within DNA strands

• interfering with DNA replication

• inhibiting nucleic acid synthesis

• inducing apoptosis in malignant cells

The drug is particularly active against rapidly dividing tumor cells.

---

Indications

Used under medical supervision for the treatment of:

• ovarian cancer

• testicular cancer

• lung cancer

• bladder cancer

• head and neck tumors

• gastric cancer

• other malignant neoplasms according to clinical protocols

---

Dosage and Administration

Cispladn 50 is administered intravenously by qualified healthcare professionals only.

Dosage is determined individually based on:

• body surface area

• type and stage of tumor

• laboratory parameters

• concomitant therapy

⚠ Self-administration is strictly prohibited.

---

Contraindications

• hypersensitivity to cisplatin or platinum compounds

• severe renal impairment

• significant bone marrow suppression

• severe hearing disorders

• pregnancy and breastfeeding (unless life-saving treatment is required)

---

Adverse Reactions

Possible side effects may include:

• nephrotoxicity

• nausea and vomiting

• myelosuppression

• peripheral neuropathy

• ototoxicity

• electrolyte imbalance

• fatigue

Regular monitoring of renal function, electrolytes, and hematological parameters is required during therapy.

---

Storage Conditions

Store at temperatures not exceeding 25°C, protected from light.
Do not freeze.
Keep out of reach of children.

---

Special Warnings

Treatment must be carried out under supervision of an oncologist. Baseline and periodic evaluation of kidney function, hearing, and blood parameters is necessary. This medicine is a potent cytotoxic agent intended for hospital or clinical use.

---

Conclusion

Cispladn 50 is a modern platinum-based antineoplastic chemotherapy drug widely used in oncology practice. Through its DNA-targeting mechanism, cisplatin remains an essential component of effective chemotherapy regimens for multiple cancer types.