Etaxedn 80 (Docetaxel) 80 mg/4 ml, Solution for Infusion

Active ingredient: Docetaxel
Strength: 80 mg / 4 ml
Dosage form: Concentrate for solution for infusion
Pharmacotherapeutic group: Antineoplastic agents — taxanes
Manufacturer: Biozenta Lifesciences Pvt. Ltd.
Country of origin: India

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Product Description

Etaxedn 80 is a cytotoxic antineoplastic medicinal product containing docetaxel, a semisynthetic taxane widely used in oncology for the treatment of various malignant tumors. It may be administered as monotherapy or as part of combination chemotherapy regimens depending on the clinical indication and therapeutic protocol.

Docetaxel acts by disrupting the microtubular network essential for mitotic and interphase cellular functions. By stabilizing microtubules and preventing their depolymerization, the drug inhibits normal cell division, leading to cell cycle arrest and programmed death of rapidly proliferating cancer cells.

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Mechanism of Action

Docetaxel:
• binds to β-tubulin;
• stabilizes microtubules;
• prevents depolymerization;
• blocks mitosis;
• induces apoptosis in tumor cells.

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Indications

Prescribed by healthcare professionals for treatment of:
• breast cancer;
• non-small cell lung cancer;
• prostate cancer;
• gastric cancer;
• head and neck cancers;
• other malignant neoplasms according to clinical judgment.

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Administration

Administered intravenously as an infusion by qualified medical personnel.
The concentrate must be diluted before administration according to medical instructions.
Dosage is calculated individually based on body surface area, diagnosis, laboratory parameters, and patient tolerance.

⚠ Self-administration is strictly prohibited.

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Contraindications

• hypersensitivity to docetaxel or formulation components;
• severe neutropenia;
• severe hepatic impairment;
• pregnancy and breastfeeding.

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Adverse Reactions

Possible side effects include:
• neutropenia and hematologic toxicity;
• nausea, vomiting, diarrhea;
• alopecia;
• peripheral neuropathy;
• edema;
• fatigue;
• allergic reactions.

Regular monitoring of blood counts is required during therapy.

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Storage Conditions

Store at temperatures not exceeding 25°C, protected from light, in original packaging.
Do not freeze.
Keep out of reach of children.

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Special Warnings

Treatment must be carried out only under supervision of an oncologist.
Assessment of liver function and hematological parameters is recommended before initiating therapy.